Engineered TAL Effector modulators for the large-scale gain-of-function screening

Recent effective use of TAL Effectors (TALEs) has provided an important approach to the design and synthesis of sequence-specific DNA-binding proteins. However, it is still a challenging task to design and manufacture effective TALE modulators because of the limited knowledge of TALE–DNA interaction...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Hanshuo, Li, Juan, Hou, Sha, Wang, Gancheng, Jiang, Mingjun, Sun, Changhong, Hu, Xiongbing, Zhuang, Fengfeng, Dai, Zhifei, Dai, Junbiao, Xi, Jianzhong Jeff
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132705/
https://ncbi.nlm.nih.gov/pubmed/24939900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku535
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