Human anti-self antibodies with high specificity from phage display libraries.

Recently we demonstrated that human antibody fragments with binding activities against foreign antigens can be isolated from repertoires of rearranged V-genes derived from the mRNA of peripheral blood lymphocytes (PBLs) from unimmunized humans. The heavy and light chain V-genes were shuffled at rand...

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Dettagli Bibliografici
Autori principali: Griffiths, A D, Malmqvist, M, Marks, J D, Bye, J M, Embleton, M J, McCafferty, J, Baier, M, Holliger, K P, Gorick, B D, Hughes-Jones, N C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC413258/
https://ncbi.nlm.nih.gov/pubmed/7679990
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