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Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene.

The nef gene, which encodes related cytoplasmic proteins in both human (HIV) and simian (SIV) immunodeficiency viruses is dispensable for viral replication in vitro. In contrast, in vivo experiments have revealed that SIV nef is required for efficient viral replication and development of AIDS in SIV...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Skowronski, J, Parks, D, Mariani, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413256/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8095017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05704.x
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