Interleukin-17 Indirectly Promotes M2 Macrophage Differentiation through Stimulation of COX-2/PGE2 Pathway in the Cancer Cells

PURPOSE: Interleukin-17 (IL-17) is a proinflammatory cytokine that plays important roles in inflammation, autoimmunity, and cancer. The purpose of this study was to determine if IL-17 indirectly regulates macrophage differentiation through up-regulation of cyclooxygenase-2 (COX-2) expression in the...

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Autores principales: Li, Qingli, Liu, Lunxu, Zhang, Qiuyang, Liu, Sen, Ge, Dongxia, You, Zongbing
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Cancer Association 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132449/
https://ncbi.nlm.nih.gov/pubmed/25038765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2014.46.3.297
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