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A Phase I Study of Oral Paclitaxel with a Novel P-Glycoprotein Inhibitor, HM30181A, in Patients with Advanced Solid Cancer

PURPOSE: The purpose of this study is to determine the maximum tolerated dose (MTD), safety, pharmacokinetics, and recommended phase II dose of an oral drug composed of paclitaxel and HM30181A, which is an inhibitor of P-glycoprotein, in patients with advanced cancers. MATERIALS AND METHODS: Patient...

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書誌詳細
主要な著者: Lee, Hyun Jung, Heo, Dae-Seog, Cho, Joo-Youn, Han, Sae-Won, Chang, Hye-Jung, Yi, Hyeon-Gyu, Kim, Tae-Eun, Lee, Se-Hoon, Oh, Do-Youn, Im, Seock-Ah, Jang, In-Jin, Bang, Yung-Jue
フォーマット: Artigo
言語:Inglês
出版事項: Korean Cancer Association 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132447/
https://ncbi.nlm.nih.gov/pubmed/25038758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2014.46.3.234
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