Considerations when investigating lncRNA function in vivo

Although a small number of the vast array of animal long non-coding RNAs (lncRNAs) have known effects on cellular processes examined in vitro, the extent of their contributions to normal cell processes throughout development, differentiation and disease for the most part remains less clear. Phenotyp...

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Autors principals: Bassett, Andrew R, Akhtar, Asifa, Barlow, Denise P, Bird, Adrian P, Brockdorff, Neil, Duboule, Denis, Ephrussi, Anne, Ferguson-Smith, Anne C, Gingeras, Thomas R, Haerty, Wilfried, Higgs, Douglas R, Miska, Eric A, Ponting, Chris P
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Developmental Biology and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132285/
https://ncbi.nlm.nih.gov/pubmed/25124674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03058
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