8-Methoxypsoralen induced mutations are highly targeted at crosslinkable sites of photoaddition on the non-transcribed strand of a mammalian chromosomal gene.

We have determined the mutational specificity of 8-methoxypsoralen photoaddition at the endogenous adenine phosphoribosyltransferase gene of Chinese hamster ovary cells hemizygous for this locus. In addition, the distribution of 8-methoxypsoralen photo-adducts was resolved in vitro at the DNA sequen...

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Vydáno v:	EMBO J
Hlavní autoři:	Sage, E, Drobetsky, E A, Moustacchi, E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8440233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05671.x
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