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Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae

Eukaryotic cells have developed mechanisms to prevent genomic instability, such as DNA damage detection and repair, control of cell cycle progression and cell death induction. The bifunctional compound furocumarin 8-methoxy-psoralen (8-MOP) is widely used in the treatment of various inflammatory ski...

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Principais autores: Lavínia Almeida Cruz, Temenouga Nikolova Guecheva, Diego Bonato, João Antônio Pêgas Henriques
Format: Artigo
Sprog:Inglês
Udgivet: Sociedade Brasileira de Genética 2012-01-01
Serier:Genetics and Molecular Biology
Fag:
DNA repair
psoralen
chromatin remodeling
histones
DNA interstrand cross-links
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600021
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