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Clonal deletion of specific thymocytes by an immunoglobulin idiotype.

We have investigated whether immunoglobulin can induce clonal deletion of thymocytes by employing two strains of transgenic mice. One strain is transgenic for an alpha/beta T cell receptor (TCR) which recognizes a processed idiotypic peptide of the lambda 2(315) light chain variable region, bound to...

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Bibliographic Details
Published in:EMBO J
Main Authors: Bogen, B, Dembic, Z, Weiss, S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8428591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05664.x
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