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Biophysical Characterisation of Calumenin as a Charged F508del-CFTR Folding Modulator
The cystic fibrosis transmembrane regulator (CFTR) is a cyclic-AMP dependent chloride channel expressed at the apical surface of epithelial cells lining various organs such as the respiratory tract. Defective processing and functioning of this protein caused by mutations in the CFTR gene results in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132023/ https://ncbi.nlm.nih.gov/pubmed/25120007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104970 |
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