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Oct-2 facilitates functional preinitiation complex assembly and is continuously required at the promoter for multiple rounds of transcription.

Octamer factor 2 (Oct-2, OTF-2, NF-A2) is an 'upstream' promoter factor that binds to the octamer motif (ATGCAAAT) implicated in control of immunoglobulin gene transcription in B-lymphocytes. We have studied the role of Oct-2 in the process of transcription initiation in vitro using both n...

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Bibliografiske detaljer
Main Authors: Arnosti, D N, Merino, A, Reinberg, D, Schaffner, W
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC413187/
https://ncbi.nlm.nih.gov/pubmed/8428575
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