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Oct-2 facilitates functional preinitiation complex assembly and is continuously required at the promoter for multiple rounds of transcription.

Octamer factor 2 (Oct-2, OTF-2, NF-A2) is an 'upstream' promoter factor that binds to the octamer motif (ATGCAAAT) implicated in control of immunoglobulin gene transcription in B-lymphocytes. We have studied the role of Oct-2 in the process of transcription initiation in vitro using both nuclear ext...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Arnosti, D N, Merino, A, Reinberg, D, Schaffner, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8428575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05641.x
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