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Opioids Enhance CXCL1 Expression and Function After Incision in Mice
Chronic opioid-consumption increases postoperative pain. Epigenetic changes related to chronic opioid use and surgical incision may be partially responsible for this enhancement. The CXCL1/CXCR2 signaling pathway implicated in several pain models and is known to be epigenetically regulated via histo...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131856/ https://ncbi.nlm.nih.gov/pubmed/24887006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2014.05.003 |
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