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Genome-wide hypermethylation coupled with promoter hypomethylation in the chorioamniotic membranes of early onset pre-eclampsia

Pre-eclampsia is the leading cause of fetal and maternal morbidity and mortality. Early onset pre-eclampsia (EOPE) is a disorder that has severe maternal and fetal outcomes, whilst its etiology is poorly understood. We hypothesize that epigenetics plays an important role to mediate the development o...

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Autors principals: Ching, Travers, Song, Min-Ae, Tiirikainen, Maarit, Molnar, Janos, Berry, Marla, Towner, Dena, Garmire, Lana X.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131767/
https://ncbi.nlm.nih.gov/pubmed/24944161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gau046
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