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NCoR REPRESSION OF LXRs RESTRICTS MACROPHAGE BIOSYNTHESIS OF INSULIN-SENSITIZING OMEGA 3 FATTY ACIDS

Macrophage-mediated inflammation is a major contributor to obesity-associated insulin resistance. The co-repressor NCoR interacts with inflammatory pathway genes in macrophages, suggesting that its removal would result in increased activity of inflammatory responses. Surprisingly, we find that macro...

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Κύριοι συγγραφείς:	Li, Pingping, Spann, Nathanael J., Kaikkonen, Minna U., Lu, Min, Oh, Da Young, Fox, Jesse N., Bandyopadhyay, Gautam, Talukdar, Saswata, Xu, Jianfeng, Lagakos, William S., Patsouris, David, Armando, Aaron, Quehenberger, Oswald, Dennis, Edward A., Watkins, Steven M., Auwerx, Johan, Glass, Christopher K., Olefsky, Jerrold M.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	2013
Θέματα:	Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4131699/ https://ncbi.nlm.nih.gov/pubmed/24074869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.054
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NCoR REPRESSION OF LXRs RESTRICTS MACROPHAGE BIOSYNTHESIS OF INSULIN-SENSITIZING OMEGA 3 FATTY ACIDS

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