Modeling the relationship between progression-free survival and overall survival: The phase 2/3 trial

The standard phase 2 trial design has changed dramatically over the last decade. Randomized phase 2 studies have essentially become the standard phase 2 design in oncology for a variety of reasons. The use of these designs is motivated by concerns regarding the use of historical data to determine if...

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Bibliografiske detaljer
Main Authors: Redman, Mary W., Goldman, Bryan H., LeBlanc, Michael, Schott, Anne, Baker, Larry
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131693/
https://ncbi.nlm.nih.gov/pubmed/23669424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2939
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