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Progression-free survival as a surrogate for overall survival in oncology trials: a methodological systematic review

BACKGROUND: Progression-free survival (PFS) is a surrogate endpoint widely used for overall survival (OS) in oncology. Validation of PFS as a surrogate must be done for each indication and each intervention. We aimed to identify all studies evaluating the validity of PFS as a surrogate for OS in onc...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Belin, Lisa, Tan, Aidan, De Rycke, Yann, Dechartres, Agnès
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250908/
https://ncbi.nlm.nih.gov/pubmed/32214230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0805-y
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