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TGF-β mediated DNA methylation in prostate cancer
Almost all tumors harbor a defective negative feedback loop of signaling by transforming growth factor-β (TGF-β). Epigenetic mechanisms of gene regulation, including DNA methylation, are fundamental to normal cellular function and also play a major role in carcinogenesis. Recent evidence demonstrate...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
AME Publishing Company
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131550/ https://ncbi.nlm.nih.gov/pubmed/25133096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2223-4683.2012.05.06 |
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