The identification of trans-associations between prostate cancer GWAS SNPs and RNA expression differences in tumor-adjacent stroma

Here we tested the hypothesis that SNPs associated with prostate cancer risk, might differentially affect RNA expression in prostate cancer stroma. The most significant 35 SNP loci were selected from Genome Wide Association (GWA) studies of ~40,000 patients. We also selected 4030 transcripts previou...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Xin, McClelland, Michael, Jia, Zhenyu, Rahmatpanah, Farah B., Sawyers, Anne, Trent, Jeffrey, Duggan, David, Mercola, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359337/
https://ncbi.nlm.nih.gov/pubmed/25638161
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