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The N-Terminal Domain of Human DNA Helicase Rtel1 Contains a Redox Active Iron-Sulfur Cluster

Human telomere length regulator Rtel1 is a superfamily II DNA helicase and is essential for maintaining proper length of telomeres in chromosomes. Here we report that the N-terminal domain of human Rtel1 (RtelN) expressed in Escherichia coli cells produces a protein that contains a redox active iron...

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Detalhes bibliográficos
Main Authors: Landry, Aaron P., Ding, Huangen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131540/
https://ncbi.nlm.nih.gov/pubmed/25147792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/285791
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