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Amyloid-beta and Alzheimer’s disease: the role of neprilysin-2 in amyloid-beta clearance

Accumulation of the amyloid-beta (Aβ) peptide is a central factor in Alzheimer’s disease (AD) pathogenesis as supported by continuing evidence. This review concisely summarizes this evidence supporting a critical role for Aβ in AD before discussing the clearance of this peptide. Mechanisms of cleara...

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Bibliografski detalji
Glavni autori: Marr, Robert A., Hafez, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131500/
https://ncbi.nlm.nih.gov/pubmed/25165447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00187
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