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Amyloid-beta and Alzheimer’s disease: the role of neprilysin-2 in amyloid-beta clearance
Accumulation of the amyloid-beta (Aβ) peptide is a central factor in Alzheimer’s disease (AD) pathogenesis as supported by continuing evidence. This review concisely summarizes this evidence supporting a critical role for Aβ in AD before discussing the clearance of this peptide. Mechanisms of cleara...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131500/ https://ncbi.nlm.nih.gov/pubmed/25165447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00187 |
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