NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model

Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are specific types of neuroendocrine tumors that originate in the adrenal medulla or sympathetic/parasympathetic paraganglia, respectively. Although these tumors are intensively studied, a very effective treatment for metastatic PHEO or PGL has not...

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Autori principali: Pacak, Karel, Sirova, Marta, Giubellino, Alessio, Lencesova, Lubomira, Csaderova, Lucia, Hudecova, Sona, Krizanova, Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131300/
https://ncbi.nlm.nih.gov/pubmed/22407736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27524
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