Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks

BACKGROUND: Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context-specific and dynamic in nature. To systematically characterize the selective...

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Библиографические подробности
Главные авторы: Tian, Ye, Zhang, Bai, Hoffman, Eric P, Clarke, Robert, Zhang, Zhen, Shih, Ie-Ming, Xuan, Jianhua, Herrington, David M, Wang, Yue
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131167/
https://ncbi.nlm.nih.gov/pubmed/25055984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0087-1
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