Maintenance treatment with the immunomodulator MGN1703, a Toll-like receptor 9 (TLR9) agonist, in patients with metastatic colorectal carcinoma and disease control after chemotherapy: a randomised, double-blind, placebo-controlled trial

PURPOSE: This phase II study evaluated the synthetic DNA-based immunomodulator and Toll-like receptor 9 agonist MGN1703 as maintenance treatment in metastatic colorectal carcinoma (mCRC). METHODS: Fifty-nine patients with mCRC and disease control after standard first-line chemotherapy were randomise...

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Detalhes bibliográficos
Main Authors: Schmoll, Hans-Joachim, Wittig, Burghardt, Arnold, Dirk, Riera-Knorrenschild, Jorge, Nitsche, Dieter, Kroening, Hendrik, Mayer, Frank, Andel, Johannes, Ziebermayr, Reinhard, Scheithauer, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Original Article – Clinical Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131138/
https://ncbi.nlm.nih.gov/pubmed/24816725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-014-1682-7
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