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Squalene synthetase activity in human fibroblasts: Regulation via the low density lipoprotein receptor

Squalene synthetase (farnesyltransferase; farnesyl diphosphate:farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21), the enzyme in the cholesterol biosynthetic pathway that converts farnesyl pyrophosphate into squalene, is subject to regulation in cultured human fibroblasts. When cholesterol-carry...

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Autores principales: Faust, Jerry R., Goldstein, Joseph L., Brown, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1979
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC413070/
https://ncbi.nlm.nih.gov/pubmed/228272
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