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Squalene synthetase activity in human fibroblasts: Regulation via the low density lipoprotein receptor

Squalene synthetase (farnesyltransferase; farnesyl diphosphate:farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21), the enzyme in the cholesterol biosynthetic pathway that converts farnesyl pyrophosphate into squalene, is subject to regulation in cultured human fibroblasts. When cholesterol-carry...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Faust, Jerry R., Goldstein, Joseph L., Brown, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1979
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/228272/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.10.5018
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