Hypoxia Preconditioned Mesenchymal Stem Cells Prevent Cardiac Fibroblast Activation and Collagen Production via Leptin

AIMS: Activation of cardiac fibroblasts into myofibroblasts constitutes a key step in cardiac remodeling after myocardial infarction (MI), due to interstitial fibrosis. Mesenchymal stem cells (MSCs) have been shown to improve post-MI remodeling an effect that is enhanced by hypoxia preconditioning (...

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Bibliographic Details
Main Authors: Chen, Panpan, Wu, Rongrong, Zhu, Wei, Jiang, Zhi, Xu, Yinchuan, Chen, Han, Zhang, Zhaocai, Chen, Huiqiang, Zhang, Ling, Yu, Hong, Wang, Jian'an, Hu, Xinyang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130526/
https://ncbi.nlm.nih.gov/pubmed/25116394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103587
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