The Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART): an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke

There is growing experimental and clinical evidence that by reducing downstream products of the mevalonate pathway other than cholesterol, HMG-CoA reductase inhibitors (‘statins’) have beneficial effects on endothelial function, coronary and cerebral blood flow, inflammation, and hemostasis. Statins...

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Main Authors: Elkind, Mitchell S. V., Sacco, Ralph L., MacArthur, Robert B., Fink, Daniel J., Peerschke, Ellinor, Andrews, Howard, Neils, Greg, Stillman, Josh, Corporan, Tania, Leifer, Dana, Cheung, Ken
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130457/
https://ncbi.nlm.nih.gov/pubmed/18705902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-4949.2008.00200.x
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