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Studies of binding of prekallikrein and Factor XI to high molecular weight kininogen and its light chain.

Prekallikrein and Factor XI have been reported to circulate as complexes with the coagulation cofactor high molecular weight (HMW)-kininogen. In this study we have shown that native HMW-kininogen possesses a strong binding site for prekallikrein and Factor XI with association constants of 3.4 x 10(7...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Thompson, R E, Mandle, R, Kaplan, A P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413037/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/291905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.10.4862
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