Toward a Comprehensive Temperature-Sensitive Mutant Repository of the Essential Genes of Saccharomyces cerevisiae

The Saccharomyces cereivisiae gene deletion project revealed that approximately 20% of yeast genes are required for viability. The analysis of essential genes traditionally relies on conditional mutants, typically temperature-sensitive (ts) alleles. We developed a systematic approach (termed “diploi...

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Bibliografski detalji
Glavni autori: Ben-Aroya, Shay, Coombes, Candice, Kwok, Teresa, O’Donnell, Kathryn A., Boeke, Jef D., Hieter, Philip
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130347/
https://ncbi.nlm.nih.gov/pubmed/18439903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.02.021
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