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RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade

The aspartic protease cathepsin D (Clan AA, Family A1) is expressed in the schistosome gut where it plays an apical role in the digestion of hemoglobin released from ingested erythrocytes. In this report, RNA interference approaches were employed to investigate the effects of knockdown of schistosom...

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Detalhes bibliográficos
Main Authors: Morales, Maria E., Rinaldi, Gabriel, Gobert, Geoffrey N., Kines, Kristine J., Tort, Jose F., Brindley, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130333/
https://ncbi.nlm.nih.gov/pubmed/18067980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.10.009
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