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RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs

Schistosoma mansoni leucine aminopeptidase (LAP) is thought to play a central role in hatching of the miracidium from the schistosome egg. We identified two discrete LAPs genes in the Schistosoma mansoni genome, and their orthologs in S. japonicum. The similarities in sequence and exon/intron struct...

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書誌詳細
主要な著者: Rinaldi, Gabriel, Morales, Maria E., Alrefaei, Yousef N., Cancela, Martín, Castillo, Estela, Dalton, John P., Tort, José F., Brindley, Paul J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705689/
https://ncbi.nlm.nih.gov/pubmed/19463860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.05.002
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