Single-dose monomeric HA subunit vaccine generates full protection from influenza challenge

Recombinant subunit vaccines are an efficient strategy to meet the demands of a possible influenza pandemic, because of rapid and scalable production. However, vaccines made from recombinant hemagglutinin (HA) subunit protein are often of low potency, requiring high dose or boosting to generate a su...

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Bibliographische Detailangaben
Hauptverfasser: Mallajosyula, Jyothi K, Hiatt, Ernie, Hume, Steve, Johnson, Ashley, Jeevan, Trushar, Chikwamba, Rachel, Pogue, Gregory P, Bratcher, Barry, Haydon, Hugh, Webby, Richard J, McCormick, Alison A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130260/
https://ncbi.nlm.nih.gov/pubmed/24378714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.27567
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