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Positive cooperativity without domains or subunits in a monomeric membrane channel

The monomeric VDAC channel shows an accelerated pH titration of its transport properties with a Hill coefficient of about 2. This manifests itself as a sharp peak in conductance noise as well as a fast change in channel selectivity with pH. On the basis of the known structure of this channel, we pro...

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Detalhes bibliográficos
Main Authors: Rostovtseva, Tatiana K., Liu, Tong-Tong, Colombini, Marco, Parsegian, V. Adrian, Bezrukov, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16628/
https://ncbi.nlm.nih.gov/pubmed/10859360
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