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Effect of Alkyl Length of Peptide–Polymer Amphiphile on Cargo Encapsulation Stability and Pharmacokinetics of 3-Helix Micelles

[Image: see text] 3-Helix micelles have demonstrated excellent in vitro and in vivo stability. Previous studies showed that the unique design of the peptide–polymer conjugate based on protein tertiary structure as the headgroup is the main design factor to achieve high kinetic stability. In this con...

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Bibliographic Details
Main Authors: Dube, Nikhil, Seo, Jai W., Dong, He, Shu, Jessica Y., Lund, Reidar, Mahakian, Lisa M., Ferrara, Katherine W., Xu, Ting
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130244/
https://ncbi.nlm.nih.gov/pubmed/24988250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm5005788
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