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Enhanced osteoblastogenesis in three-dimensional collagen gels

Growth and differentiation of osteoblasts are often studied in cell cultures. In vivo, however, osteoblasts are embedded within a complex three-dimensional (3D) microenvironment, which bears little relation to standard culture flasks. Our study characterizes osteoblast-like cells cultured in 3D coll...

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Bibliografiske detaljer
Main Authors: Matthews, Brya G, Naot, Dorit, Callon, Karen E, Musson, David S, Locklin, Rachel, Hulley, Philippa A, Grey, Andrew, Cornish, Jillian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130130/
https://ncbi.nlm.nih.gov/pubmed/25120910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2014.55
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