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Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat.

The regulation of human immunodeficiency virus type 1 (HIV-1) gene expression in response to Tat is dependent on an element downstream of the HIV-1 transcriptional initiation site designated the trans-activating region (TAR). TAR forms a stable stem-loop RNA structure in which a 3-nt bulge structure...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wu-Baer, F, Sigman, D, Gaynor, R B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41297/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7153
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