The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes

The mechanisms generating epileptic neuronal networks following insults such as severe seizures are unknown. We have previously shown that interfering with the function of the neuron-restrictive silencer factor (NRSF/REST), an important transcription factor that influences neuronal phenotype, attenu...

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Autors principals: McClelland, Shawn, Brennan, Gary P, Dubé, Celine, Rajpara, Seeta, Iyer, Shruti, Richichi, Cristina, Bernard, Christophe, Baram, Tallie Z
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129437/
https://ncbi.nlm.nih.gov/pubmed/25117540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01267
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