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Neuron-restrictive silencer factor-mediated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy
OBJECTIVE: Enduring, abnormal expression and function of the ion channel hyperpolarization-activated cyclic-AMP gated channel type 1 (HCN1) occurs in temporal lobe epilepsy (TLE). We examined the underlying mechanisms, and queried if interfering with these mechanisms could modify disease course. MET...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177145/ https://ncbi.nlm.nih.gov/pubmed/21905079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22479 |
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