Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels

Many genetic variants associated with human disease have been found to be associated with alterations in mRNA expression. Although it is commonly assumed that mRNA expression changes will lead to consequent changes in protein levels, methodological challenges have limited our ability to test the deg...

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Detalhes bibliográficos
Main Authors: Hause, Ronald J., Stark, Amy L., Antao, Nirav N., Gorsic, Lidija K., Chung, Sophie H., Brown, Christopher D., Wong, Shan S., Gill, Daniel F., Myers, Jamie L., To, Lida Anita, White, Kevin P., Dolan, M. Eileen, Jones, Richard Baker
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129400/
https://ncbi.nlm.nih.gov/pubmed/25087611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.07.005
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