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Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells()

Chemokine CXCL12 promotes CXCR4-dependent chemotaxis of cancer cells to characteristic organs and tissues, leading to metastatic disease. This study was designed to investigate how cells expressing CXCR7 regulate chemotaxis of a separate population of CXCR4 cells under physiologic conditions in whic...

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Autori principali: Torisawa, Yu-suke, Mosadegh, Bobak, Bersano-Begey, Tommaso, Steele, Jessica M., Luker, Kathryn E., Luker, Gary D., Takayama, Shuichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128891/
https://ncbi.nlm.nih.gov/pubmed/20871938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ib00041h
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