QKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2

Cancer stem cells (CSCs) may contribute to tumor initiation, distant metastasis and chemo-resistance. One of RNA-binding proteins, Quaking (QKI), was reported to be a tumor suppressor. Here we showed that reduced QKI levels were observed in many human oral cancer samples. Moreover further reduction...

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Bibliografiske detaljer
Main Authors: Lu, Wei, Feng, Feixue, Xu, Jinke, Lu, Xiaozhao, Wang, Shan, Wang, Lifeng, Lu, Huanyu, Wei, Mengying, Yang, Guodong, Wang, Li, Lu, Zifan, Liu, Yanpu, Lei, Xiaoying
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128860/
https://ncbi.nlm.nih.gov/pubmed/24918581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29502
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