An Automated Three-Dimensional Detection and Segmentation Method for Touching Cells by Integrating Concave Points Clustering and Random Walker Algorithm

Characterizing cytoarchitecture is crucial for understanding brain functions and neural diseases. In neuroanatomy, it is an important task to accurately extract cell populations' centroids and contours. Recent advances have permitted imaging at single cell resolution for an entire mouse brain u...

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Bibliographic Details
Main Authors: He, Yong, Meng, Yunlong, Gong, Hui, Chen, Shangbin, Zhang, Bin, Ding, Wenxiang, Luo, Qingming, Li, Anan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128780/
https://ncbi.nlm.nih.gov/pubmed/25111442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104437
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