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Solution Structure of a Sponge-Derived Cystine Knot Peptide and Its Notable Stability

A novel cystine knot peptide, asteropsin E (ASPE), was isolated from an Asteropus sp. marine sponge. The primary, secondary, and tertiary structures of ASPE were determined by high-resolution 2D NMR spectroscopy (900 MHz). With the exception of an N-terminal modification, ASPE shares properties with...

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Autores principales: Li, Huayue, Su, Mingzhi, Hamann, Mark T., Bowling, John J., Kim, Hyung Sik, Jung, Jee H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128683/
https://ncbi.nlm.nih.gov/pubmed/24499386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400899a
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