Tumor suppressor p16(INK4A)/Cdkn2a alterations in 7, 12-dimethylbenz(a)anthracene (DMBA)-induced hamster cheek pouch tumors

The prevalence of p16(INK4A)/CDKN2A genetic alterations in human oral cancers indicates that the p16 gene could be a potent and appropriate target for novel intervention. Chemically induced hamster cheek pouch (HCP) tumors are highly similar to human oral cancers in both histology and genetics and m...

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Autori principali: Li, Junan, Warner, Blake, Casto, Bruce C., Knobloch, Thomas J., Weghorst, Christopher M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128555/
https://ncbi.nlm.nih.gov/pubmed/18247379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20424
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