Complex pattern of interaction between in utero hypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function

BACKGROUND: Infants born preterm commonly suffer from a combination of hypoxia-ischemia (HI) and infectious perinatal inflammatory insults that lead to cerebral palsy, cognitive delay, behavioral issues and epilepsy. Using a novel rat model of combined late gestation HI and lipopolysaccharide (LPS)-...

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Main Authors: Jantzie, Lauren L, Corbett, Christopher J, Berglass, Jacqueline, Firl, Daniel J, Flores, Julian, Mannix, Rebekah, Robinson, Shenandoah
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128546/
https://ncbi.nlm.nih.gov/pubmed/25082427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-131
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