Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate

BACKGROUND: Neuromyelitis optica (NMO, Devic syndrome) is associated with antibodies to aquaporin-4 (NMO-IgG/AQP4-Ab) in the majority of cases. NMO-IgG/AQP4-Ab seropositivity in patients with NMO and its spectrum disorders has important differential diagnostic, prognostic and therapeutic implication...

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Detalhes bibliográficos
Main Authors: Jarius, Sven, Paul, Friedemann, Fechner, Kai, Ruprecht, Klemens, Kleiter, Ingo, Franciotta, Diego, Ringelstein, Marius, Pache, Florence, Aktas, Orhan, Wildemann, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128531/
https://ncbi.nlm.nih.gov/pubmed/25074611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-129
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