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Tetrasubstituted pyrazinones derived from the reaction of praziquantel with N-bromosuccinimide
When praziquantel was exposed to N-bromosuccinimide in the presence of ethanol, a tricyclic 3-bromo-1-ethoxy pyrazinone was formed. From this and the analogous 1,3-dibromopyrazinone, a small library of 3-alkylamino-1-ethoxy, 1,3-dialkoxy, 3-alkoxy-1-bromo, and 3-alkylamino-1-bromo substituted pyrazi...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4128413/ https://ncbi.nlm.nih.gov/pubmed/25125709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.06.083 |
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