Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution

An outbreak of the fungal pathogen Cryptococcus gattii began in the Pacific Northwest (PNW) in the late 1990s. This outbreak consists of three clonal subpopulations: VGIIa/major, VGIIb/minor, and VGIIc/novel. Both VGIIa and VGIIc are unique to the PNW and exhibit increased virulence. In this study,...

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Autores principales: Billmyre, R. Blake, Croll, Daniel, Li, Wenjun, Mieczkowski, Piotr, Carter, Dee A., Cuomo, Christina A., Kronstad, James W., Heitman, Joseph
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128362/
https://ncbi.nlm.nih.gov/pubmed/25073643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01494-14
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