Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution

An outbreak of the fungal pathogen Cryptococcus gattii began in the Pacific Northwest (PNW) in the late 1990s. This outbreak consists of three clonal subpopulations: VGIIa/major, VGIIb/minor, and VGIIc/novel. Both VGIIa and VGIIc are unique to the PNW and exhibit increased virulence. In this study,...

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Autori principali: Billmyre, R. Blake, Croll, Daniel, Li, Wenjun, Mieczkowski, Piotr, Carter, Dee A., Cuomo, Christina A., Kronstad, James W., Heitman, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128362/
https://ncbi.nlm.nih.gov/pubmed/25073643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01494-14
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